Jackie Brighton's life as a succubus is going great: she's gone from mousy to bombshell, and although she has to have sex every forty-eight hours or die, she has two hot guys — the vampire Zane and the angel Noah — to scratch her Itch. But then her Itch accelerates to every twenty-four hours, and she's suddenly waking people's unconscious just by touching them. Something's out of control so she and Remy, her mentor, go on an adventure-filled road trip to New Orleans to consult with the oldest succubus in the United States. Jackie learns she's been cursed by a vampire queen — and reversing the curse demands a price she's not willing to pay.

Jackie Brighton has a problem. First she slept with a hot guy she met in a bar after too many martinis, then she woke up in a dumpster, where a mugger had left her for dead. Except her one-night stand turned out to be an angel named Noah, and her mugger turned out to be a vampire named Zane — and the combination of angel-sex and vampire-bite has turned her into a succubus. The upside of being a succubus? She's suddenly a bombshell with hoards of men panting after her, which is a very good thing — because the downside is The Itch: she needs sex constantly. Sure, it might sound like fun. But Jackie's picky about who she sleeps with, yet if she doesn't have sex regularly and frequently, she'll literally die! When Jackie's pulled into Noah's and Zane's pursuit of an ancient halo that will give the Heavenly Host or the Infernal Host ultimate power in the world, she now has two hot guys to scratch her Itch — unless she gets destroyed in the battle for the halo, first.