After the fallout (nuclear and otherwise) of Deadpool's antics out in Arizona, the federal government is faced with an impossible question; What to do with Deadpool? Luckily, Deadpool's gamma-powered legal defense team provided an answer: Stick him in an institution! When you think about it, it might be the only solution — aftr all he really does need some professional help as well as protection from the enemy: himself.

Deadpool has become fixated on achieving the one thing that's always been beyond his reach: death. Not an easy thing for an unkillable man to achieve, but that's not gonna stop him from trying. but first, he must figure out the all-important question: how? What in the world can kill Deadpool? It has to be big. It has to be powerful beyond description. It has to be... green? Plus: Macho Gomez is back! And this time, he's brought friends. His friends? Nope — Deadpool's friends. And every single one of them has an axe to grind with our boy Wade for how he's treated them in the past. no, really — they have axes!

Would the real Wade Wilson please stand up? Deadpool returns to America, but he's not coming home alone! When a collection of Deadpool's discarded body parts meld to form an evil clone, the Merc With a Mouth faces off against himself for the crown of most hated former mercenary turned super hero turned pirate turned intergalactic bounty hunter. But their explosive confrontation brings the NYPD, Interpol and even Captain America bearing down on Deadpool, and he'll have to convince them all there's an even crazier, less principled version of himself on the loose!

Deadpool, everyone's favorite fun-loving killer-for-hire, is back in business, taking on a new gig — in space! Will this job cement his rep as the best merc in the solar system, or will things like lack of oxygen and zero-gravity throw him off his game? One word: Maybe! Plus: The Wrecker, an immensely powerful psychopath, is on the loose and wreaking havoc. There's only one person to call: Deadpool! And did you hear? There's a new player in town, and this cat is baaaaad. He's got crazy spaceguns, an intergalactic hooptie, a rep that's getting bigger by the day and just about the coolest name ever. And he's here on Earth to let everybody know, starting with Deadpool!

Deadpool gets the chance of a lifetime to join the Secret Avengers, but things aren't as they seem. Deadpool? An Avenger? Come on! When the evil Dr. Bong clones Steve Rogers' clandestine team of heroes to steal weapons of mass destruction, Wade must fight alongside the real Secret Avengers against the fake Secret Avengers and try to not to shoot the wrong guy! Plus: Deadpool gets hired by a bunch of good Draculas to fight some bad Draculas — and no, they don't sparkle! Wade takes on the rebel vampires in a hospital fight and even manages to rescue the girl! Wait, sorry, he shoots her in the leg! Collecting DEADPOOL.

Deadpool and Spider-Man team up (yes, team up) to combat the unstoppable killing machine known as HIT-MONKEY! Yes, HIT-MONKEY. But can Deadpool do what it takes to rid New York of this terrifying new menace, or will he wilt under the monkey's soulful gaze? Plus: Bear witness as the legend of Hit-Monkey is born!

Deadpool has ceased to exist, he's given his good-byes, he's driven his car into the ocean. They'll think he's dead, but he'll sail away. Then, he becomes a pirate! Collects Deadpool

The Merc with a Mouth is back, even deadlier and more deranged than before! The planet has been invaded by Skrulls, everything's gone topsy-turvy... but, in Deadpool's world, that just means it's Monday! Crazy times call for crazy men, but c'mon, this guy's insane! Like it or not, Deadpool may be the only person on the planet who can save us... but who's to say he wants to? An explosive debut story by writer Daniel Way (Wolverine: Origins, Ghost Rider, Bullseye: Greatest Hits) and fan-favorite artist Paco Medina (New Warriors, New X-Men)! Deadpool: His madness is his method! You won't want to miss it! Collects Deadpool №1-5.